Unlocking LIpid Biology.
Building Precision MEdicines.

Turning lipid biology into transformative medicines

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Lime Therapeutics is a biotechnology company developing first-in-class small-molecule therapies for diseases driven by cellular stress and dysfunction. At the heart of our drug discovery is LipidSense, our proprietary platform that enables us to interrogate lipid biology at unprecedented resolution and uncover disease-driving mechanisms that can be translated into novel therapeutic approaches.

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Lime applies this discovery engine across oncology, cardiometabolic disease, and neurodegenerative and lysosomal storage disorders, where alterations in cellular lipid metabolism and stress responses play fundamental roles in disease progression, treatment resistance, and cellular dysfunction. Our approach integrates deep biological insight, quantitative lipid profiling, and small molecule drug discovery to identify and develop therapeutics against previously underexploited targets.

We are building a pipeline of oral, small molecule medicines designed to address important biological drivers of disease and deliver meaningful improvements for patients with limited treatment options.

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Our mission is to transform insights from lipid biology into differentiated medicines for diseases with significant unmet need.